Bioactive Fraction of Geopropolis from Melipona scutellaris Decreases Neutrophils Migration in the Inflammatory Process: Involvement of Nitric Oxide Pathway

Figure 5

Effect of the ethanolic extract of geopropolis (EEGP) and aqueous fraction (AF) on the expression of ICAM-1 (a) and nitrite levels (b) 4 h after the injection of 500 μg/cavity of carrageenan (Cg) in the peritoneal cavity. Mice were pretreated with vehicle (saline and carrageenan), EEGP, or aqueous fraction (10 mg/kg, s.c.). The data are expressed as mean ± SEM, 𝑛=5. Symbols indicate statistical difference (𝑃<0.05, Tukey test). ^#Compared to the saline group; *compared to the carrageenan group.

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