Evaluation of Antidiabetic Activity and Associated Toxicity of Artemisia afra Aqueous Extract in Wistar Rats

Table 5

Effect of aqueous extract of Artemisia  afra on some liver function parameters of diabetic rats (𝑛=6±SE).

	Control	Diabetic	Diabetic + Artemisia  afra (mg/kg body weight)
			50	100	200
Liver-to-body weight ratio (%)	2.41±0.19^a	3.96±0.24^b	2.41±0.20^a	2.50±0.46^a	2.60±0.18^a
Total bilirubin (μmol/L)	0.50±0.07^a	1.89±0.11^b	0.58±0.03^a	0.63±0.08^a	0.63±0.07^a
Albumin (g/L)	24.94±1.22^a	19.16±0.98^b	24.52±1.22^a	24.20±1.00^a	23.90±1.27^a
Globulin (g/L)	53.66±3.40^a	44.25±0.99^b	52.40±1.80^a	49.72±1.08^a	49.18±1.07^a
Serum alkaline phosphatase (U/L)	12.34±1.70^a	30.16±2.01^b	13.71±1.20^a	14.53±1.25^a	15.08±1.80^a
Serum 𝛾-glutamyl transferase (U/L)	3.32±0.02^a	8.11±0.08^b	3.47±0.06^a	3.48±0.06^a	3.48±0.08^a
Serum alanine transaminase (U/L)	16.71±1.98^a	37.54±1.23^b	19.21±2.47^a	20.19±1.90^a	20.44±1.93^a
Serum aspartate transaminase (U/L)	11.29±1.53^a	22.30±1.23^b	11.75±1.30^a	12.62±1.00^a	13.49±1.02^a

Values carrying different superscripts from the control for each parameter are significantly different (𝑃<0.05).