Evaluation of Antidiabetic Activity and Associated Toxicity of Artemisia afra Aqueous Extract in Wistar Rats

Table 6

Effect of aqueous extract of Artemisia  afra on some kidney function parameters of diabetic rats (𝑛=6±SE).

	Control	Diabetic	Diabetic + Artemisia  afra (mg/kg body weight)
			50	100	200
Kidney-to-body weight ratio (%)	5.32±0.35^a	9.91±0.14^b	5.87±0.46^a	7.84±0.21^c	8.57±0.19^d
Calcium (mmol/L)	1.49±0.04^a	2.99±0.08^b	1.56±0.03^a	1.87±0.05^c	1.98±0.04^c
Creatinine (mg/dL)	31.52±0.84^a	59.25±0.50^b	33.49±1.00^a	43.34±0.48^c	47.28±0.38^d
Urea (mg/dL)	36.42±3.50^a	163.32±5.31^b	41.72±1.36^a	70.60±2.08^c	81.29±2.29^d
Uric acid (mg/dL)	5.03±0.21^a	9.74±0.16^b	5.29±0.18^a	6.92±0.09^c	6.97±0.08^c

Values carrying different superscripts from the control for each parameter are significantly different (𝑃<0.05).