Research Article

Protective Effect of Free and Bound Polyphenol Extracts from Ginger (Zingiber officinale Roscoe) on the Hepatic Antioxidant and Some Carbohydrate Metabolizing Enzymes of Streptozotocin-Induced Diabetic Rats

Table 1

Effect of administration of polyphenols from Z. officinale on the fasting blood glucose of normal and streptozotocin-diabetic rats.

GroupGlucose (mmol/L)
Day 1Day 14Day 28

Normal control 4.51 ± 0.18a4.44 ± 0.20a4.78 ± 0.36a
Diabetic control18.34 ± 0.47b21.8 ± 0.67b24.87 ± 1.13b
Diabetic + free polyphenol20.44 ± 0.72b21.38 ± 0.95b12.22 ± 1.63d
Diabetic + bound polyphenol21.8 ± 0.67b22.46 ± 0.91b16.56 ± 0.95c
Diabetic + glibenclamide20.48 ± 0.83b17.56 ± 0.39c9.22 ± 0.78d

Values are mean S.E.M. of 8 rats per group. Test values down the vertical columns carrying different superscripts for each day are significantly different (P < 0.05).