Protective Effect of Free and Bound Polyphenol Extracts from Ginger (Zingiber officinale Roscoe) on the Hepatic Antioxidant and Some Carbohydrate Metabolizing Enzymes of Streptozotocin-Induced Diabetic Rats

Table 4

Effect of administration of polyphenols from Z. officinale on liver function parameters of normal and streptozotocin-diabetic rats.

Group	Liver function
	AST (U/L)	ALT (U/L)	ALB (mg/dL)	BIL (mg/dL)
Normal control	67.2 ± 4.67^a	131.1 ± 9.44^a	5.29 ± 1.10^a	3.30 ± 0.54^a
Diabetic control	191.4 ± 22.94^b	251.4 ± 36.96^b	5.84 ± 1.50^a	4.84 ± 0.53^a
Diabetic + free	95.60 ± 15.91^c	156.6 ± 13.20^c	5.04 ± 0.93^a	3.10 ± 0.49^a
Diabetic + bound	121.0 ± 3.54^d	181.2 ± 7.87^d	6.27 ±0.71^a	4.15 ± 0.72^a
Diabetic + GBN	83.3 ± 5.54^c	136.5 ± 11.92^a	4.89 ± 0.87^a	2.31 ± 0.60^a

Values are mean ± S.E.M. of 8 rats per group. Test values down the vertical columns carrying different superscripts for each parameter are significantly different (P < 0.05). AST: aspartate aminotransferase, ALT: alanine aminotransferase, ALB: albumin, BIL: bilirubin.