Oral Panax notoginseng Preparation for Coronary Heart Disease: A Systematic Review of Randomized Controlled Trials

Table 3

Analysis of efficacy of angina pectoris.

Angina pectoris (comparison)	Intervention group		Control group		Weight (%)	MD	95% CI
	Mean	SD	Mean	SD
(1) Angina pectoris frequency
Panax notoginseng preparation and conventional therapy versus conventional therapy (times/week)
Du and Chen 2009 [21]	3.24	0.61	5.63	0.92	33.6	−2.39	[−2.68, −2.10]
Kuang et al. 2011 [33]	3.53	0.61	6.83	1.92	14.1	−3.30	[−3.72, −2.88]
Song et al. 2005 [26]	0.75	0.79	1.36	1.31	32.4	−0.61	[−1.03, −0.19]
Wei 2010 [29]	4.27	0.87	6.58	0.75	34.0	−2.31	[−2.55, −2.07]
	Overall (REM, 𝐼^2=96%, 𝑁=572)				100	−2.16	[−3.02, −1.30]
Sensitive analysis (excluded Song et al. 2005 [26] Kuang et al. [33])	Overall (FEM, 𝐼^2=0%, 𝑁=292)					−2.34	[−2.53, −2.16]
Panax notoginseng preparation and conventional therapy versus conventional therapy (times/day)
Yang 2012 [36]	1.22	0.97	3.98	1.89	28	−2.76	[−3.87, −1.65]
(2) Angina pectoris duration (minute/time)
Panax notoginseng preparation and conventional therapy versus conventional therapy
Du and Chen 2009 [21]	2.86	0.72	4.82	0.63	60.7	−1.96	[−2.21, −1.71]
Kuang et al. 2011 [33]	2.23	0.62	4.78	0.83	45.4	−2.55	[−2.76, −2.34]
Wei 2010 [29]	4.56	1.08	6.32	1.05	39.3	−1.76	[−2.07, −1.45]
	Overall (REM, 𝐼^2=91%, 𝑁=472)				100	−2.10	[−2.58, −1.62]
Sensitive analysis (excluded Kuang et al., [33])	Overall (FEM, 𝐼^2=0%, 𝑁=292)					−1.88	[−2.08, −1.69]
(3) Dosage of nitroglycerol
Panax notoginseng preparation and conventional therapy versus conventional therapy (mg/week)
Du and Chen 2009 [21]	2.94	2.26	4.26	1.94	53.0	−1.32	[−2.10, −0.54]
Song et al. 2005 [26]	2.95	2.25	3.87	1.97	47.0	−0.92	[−1.75, −0.09]
	Overall (FEM, 𝐼^2=0%, 𝑁=212)				100	−1.13	[−1.70, −0.56]
Panax notoginseng preparation and conventional therapy versus conventional therapy (mg/day)
Yang 2012 [36]	1.3	0.4	5.4	2.8	100	−4.10	[−5.58, −2.62]

FEM: fixed effects model; REM: random effects model; MD: mean difference; CI: credibility interval.