| Study ID | ADs |
| Du and Chen 2009 [21] | No abnormal changes appeared and no Ads was reported in the trial. | Ge and Zhao 2010 [22] | Blood regular test, urine regular test, and blood biochemistry test had no changes compared with the previous. | Han and Chen 2008 [23] | No serious Ads were reported in the trial; blood, urine, and stool routine tests, blood biochemistry test had no changes comparing with the previous. | Ji and Zhang 2003 [24] | Blood, urine, and stool routine tests, and blood biochemistry test had no changes compared with the previous. No Ads was reported in the trial. | Meng 2003 [25] | Reduction of blood pressure and increasement of heart rate: intervention group: 0/60; control group: 5/20. RR: 0.03. 95% CI: [0.00, 0.54]. | Wei 2010 [29] | Blood, urine, and stool routine tests, and blood biochemistry test had no changes compared with the previous. No Ads was reported in the trial. | Yan 2005 [30] | Nausea: intervention group (1/24), control group (0/24), RR: 3.0, 95% CI: [0.13, 70.16]. Dizziness: intervention group (0/24), control group (1/24), RR: 0.33, 95% CI: [0.01, 7.80]. Vomit: intervention group (0/24), control group (1/24), RR: 0.33, 95% CI: [0.01, 7.80]. | Yu 2010 [31] | Erythra: intervention group (1/50), control group: (0/50). RR: 3.00; 95% CI: [0.13, 71.92]. | Kuang et al. 2011 [33] | No abnormal changes appeared and no Ads was reported in the trial. |
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