Research Article

Effects of Pretreatment with a Combination of Melatonin and Electroacupuncture in a Rat Model of Transient Focal Cerebral Ischemia

Figure 1

Schematic overview of the experimental procedures in a rat model of transient MCAO. Two groups are included in the experiment. The horizontal line represents time. A single i.p. injection of the vehicle and melatonin was given 30 minutes before transient MCAO in control and MEA groups, respectively. Whilst the rats were under anesthesia, sham and real EA were given daily 6 days before transient MCAO in the sham EA group and EA group, respectively. All the rats were killed 24 hours after transient MCAO for determination of brain infarct volume, cerebral edema ration and tissue processing.
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