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Evidence-Based Complementary and Alternative Medicine
Volume 2013 (2013), Article ID 957030, 13 pages
http://dx.doi.org/10.1155/2013/957030
Research Article

Metabolism of Genipin in Rat and Identification of Metabolites by Using Ultraperformance Liquid Chromatography/Quadrupole Time-of-Flight Tandem Mass Spectrometry

1Experiment Center for Teaching and Learning, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
2School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
3Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China

Received 17 October 2012; Accepted 10 February 2013

Academic Editor: Wei Jia

Copyright © 2013 Yue Ding et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [3 citations]

The following is the list of published articles that have cited the current article.

  • Yue Ding, Yong Zhang, Tong Zhang, Ming Peng, Jian-Sheng Tao, and Guang Ji, “ A validated HPLC-MS/MS method for determination of genipin-1- o -glucuronic acid in rat plasma after administration of genipin and its application to a pharmacokinetic study ,” Biomedical Chromatography, 2013. View at Publisher · View at Google Scholar
  • Q.-S. Wang, J.-S. Tian, Y.-L. Cui, and S. Gao, “Genipin is active via modulating monoaminergic transmission and levels of brain-derived neurotrophic factor (BDNF) in rat model of depression,” Neuroscience, 2014. View at Publisher · View at Google Scholar
  • Jenna Pekkinen, Natalia N. Rosa, Otto-Ilari Savolainen, Pekka Keski-Rahkonen, Hannu Mykkanen, Kaisa Poutanen, Valerie Micard, and Kati Hanhineva, “Disintegration of wheat aleurone structure has an impact on the bioavailability of phenolic compounds and other phytochemicals as evidenced by altered urinary metabolite profile of diet-induced obese mice,” Nutrition & Metabolism, vol. 11, 2014. View at Publisher · View at Google Scholar