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Evidence-Based Complementary and Alternative Medicine
Volume 2013 (2013), Article ID 957030, 13 pages
Metabolism of Genipin in Rat and Identification of Metabolites by Using Ultraperformance Liquid Chromatography/Quadrupole Time-of-Flight Tandem Mass Spectrometry
1Experiment Center for Teaching and Learning, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
2School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
3Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
Received 17 October 2012; Accepted 10 February 2013
Academic Editor: Wei Jia
Copyright © 2013 Yue Ding et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Citations to this Article [6 citations]
The following is the list of published articles that have cited the current article.
- Yue Ding, Yong Zhang, Tong Zhang, Ming Peng, Jian-Sheng Tao, and Guang Ji, “ A validated HPLC-MS/MS method for determination of genipin-1- o -glucuronic acid in rat plasma after administration of genipin and its application to a pharmacokinetic study ,” Biomedical Chromatography, 2013.
- Q.-S. Wang, J.-S. Tian, Y.-L. Cui, and S. Gao, “Genipin is active via modulating monoaminergic transmission and levels of brain-derived neurotrophic factor (BDNF) in rat model of depression,” Neuroscience, 2014.
- Hongxin Cao, Aihua Zhang, Fang-mei Zhang, Qin-qin Wang, He Zhang, Yan-hua Song, Ying Zhou, Hui Sun, Guang-li Yan, Ying Han, and Xijun Wang, “Ultra-performance liquid chromatography tandem mass spectrometry combined with automated MetaboLynx analysis approach to screen the bioactive components and their metabolites in Wen-Xin-Formula,” Biomedical Chromatography, vol. 28, no. 12, pp. 1774–1781, 2014.
- Jenna Pekkinen, Natalia N. Rosa, Otto-Ilari Savolainen, Pekka Keski-Rahkonen, Hannu Mykkanen, Kaisa Poutanen, Valerie Micard, and Kati Hanhineva, “Disintegration of wheat aleurone structure has an impact on the bioavailability of phenolic compounds and other phytochemicals as evidenced by altered urinary metabolite profile of diet-induced obese mice,” Nutrition & Metabolism, vol. 11, 2014.
- Ran Zuo, Wei Ren, Bao-Lin Bian, Hong-Jie Wang, Yao-Nan Wang, Hao Hu, Hai-Yu Zhao, and Nan Si, “Metabolic fate analysis of Huang–Lian–Jie–Du Decoction in rat urine and feces by LC–IT-MS combining with LC–FT-ICR-MS: a feasible strategy for the metabolism study of Chinese medical formula,” Xenobiotica, pp. 1–17, 2015.
- Heyun Zhu, Kaishun Bi, Fei Han, Jiao Guan, Xiaoshu Zhang, Xinjuan Mao, Longshan Zhao, Qing Li, Xiaohong Hou, and Ran Yin, “Identification of the absorbed components and metabolites of Zhi-Zi-Da-Huang decoction in rat plasma by ultra-high performance liquid chromatography coupled with quadrupole-time-of-flight mass spectrometry,” Journal of Pharmaceutical and Biomedical Analysis, 2015.