Research Article

Metabolism of Genipin in Rat and Identification of Metabolites by Using Ultraperformance Liquid Chromatography/Quadrupole Time-of-Flight Tandem Mass Spectrometry

Figure 5

The extracted ion chromatogram of m/z 225 of bile treated accordingly to experimental schemes. (a) the standard solution with genipin at concentration of 50 ng/mL; (b) the drug-containing bile; (c) the drug-containing urine hydrolyzed by sulfatase; (d) the drug-containing urine hydrolyzed with β-glucuronidase.
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(a)
957030.fig.005b
(b)
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(c)
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(d)