Research Article

NCCAM/NCI Phase 1 Study of Mistletoe Extract and Gemcitabine in Patients with Advanced Solid Tumors

Table 5

Pharmacokinetics of gemcitabine (cycle 1) and gemcitabine plus mistletoe (cycle 3).

Cycle 1
Median
(25th%, 75th%)
Cycle 3
Median
(25th%, 75th%)
value
Signed rank test

Gemcitabine
AUC (min * nmol/mL)
664
(514, 870)
670
(625, 851)
0.97
Gemcitabine
Average Cp (nmol/mL)
47.7
(42.7, 64.6)
49.7
(45.7, 53.8)
0.85