Research Article

Higenamine Combined with [6]-Gingerol Suppresses Doxorubicin-Triggered Oxidative Stress and Apoptosis in Cardiomyocytes via Upregulation of PI3K/Akt Pathway

Figure 5

HG/[6]-GR inhibited the collapse of MMP in NRCs induced by DOX. After 24 h of treatment, cells were coincubated with the fluorescence probe JC-1 for 10 min at 37°C; images (original magnification ×400, bar 100 μm) were scanned by confocal laser microscopy and the ratios of red/green fluorescent densities from 8 random fields were calculated for each sample. Data were expressed as mean SD. * DOX group versus control group, # DOX+HG/[6]-GR group versus DOX group.
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