Proteomic Analysis of the Effect of Fuzheng Huayu Recipe on Fibrotic Liver in Rats

Table 4

Identification of 15 differentially expressed proteins among normal, model, and FZHY groups.

Spot number	NCBI GI	Molecular; weight	PI	Sequence; coverage %	Protein description
733^A	6978607	60062	7.07	21	Catalase ↓
967^A	203361	23220	4.63	26	Clathryn light chain ↓
1069^A	149021114	53725	5.06	31	Vimentin isoform CRA_b ↑
1683^A	408807	33938	5.40	38	Regucalcin ↓
2563^A	58331159	25388	8.42	18	Glutathione S-transferase Yc2 subunit ↑
947^AB	14192935	54994	7.94	29	Aldehyde dehydrogenase 1 family, member A1; ↑
1194^AB	149021114	53725	5.06	30	Vimentin isoform CRA_b ↑
1234^AB	109492380	59163	5.67	22	Gamma-actin ↑
1334^AB	14389299	53757	5.06	21	Vimentin ↑
1747^AB	1619606	40035	8.66	24	Fructose-bisphosphate aldolase B ↓
2341^AB	20302063	37639	6.18	20	Aldo-keto reductase family 1, member D1 ↓
2549^AB	149030911	44800	6.08	14	S-adenosylhomocysteine hydrolase, isoform ↑
2556^AB	256089	83606	5.06	10	HSP90 ↑
706^B	149059759	60121	5.38	15	Chaperonin subunit 8(theta) ↓
1208^B	149021114	53725	5.06	24	Vimentin isoform CRA_b ↓

Ameans Pattern A, in which the spot proteins differentially expressed between normal and model groups.^Bmeans Pattern B, in which the spot proteins differentially between FZHY and model groups. The upward arrow (↑) or downward arrow (↓) indicates the spot proteins in the model group had increased or decreased expression compared to ones in normal or FZHY group, respectively.