Dangguijakyak-San Protects against 1-Methyl-4-phenyl-1,2,3,6,-tetrahydropyridine-Induced Neuronal Damage via Anti-Inflammatory Action
Figure 4
Inhibitory effect of DJS on MPTP-induced bradykinesia in a mouse model of PD. DJS at 50 mg/kg/day for 5 days was administered, and MPTP at 20 mg/kg was injected four times at 2 h interval on the day of last DJS treatment. On the first day of MPTP injection, the pole test was performed. The times to turn (T-LA) and the times to completely downward and to arrive at the floor (b) were recorded. Each column represents the mean ± SEM from ten replications. Data are expressed as percentages relative to the controls. ### significantly different from the control group. ***, * significantly different from the MPTP only treated group.