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Evidence-Based Complementary and Alternative Medicine
Volume 2013 (2013), Article ID 983609, 10 pages
Empetrum nigrum var. japonicum Extract Suppresses Ultraviolet B-Induced Cell Damage via Absorption of Radiation and Inhibition of Oxidative Stress
1School of Medicine and Institute for Nuclear Science and Technology, Jeju National University, Jeju 690-756, Republic of Korea
2Halla Arboretum, Jeju 690-121, Republic of Korea
3Biospectrum Life Science Institute, Seongnam 442-13, Republic of Korea
Received 5 July 2012; Revised 21 December 2012; Accepted 27 December 2012
Academic Editor: Guillermo Schmeda-Hirschmann
Copyright © 2013 Ki Cheon Kim et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- A. F. Bais, C. S. Zerefos, C. Meleti, I. C. Ziomas, and K. Tourpali, “Spectral measurements of solar UVB radiation and its relations to total ozone, SO2, and clouds,” Journal of Geophysical Research, vol. 98, no. 3, pp. 5199–5204, 1993.
- G. L. Manney, M. L. Santee, M. Rex, et al., “Unprecedented Arctic ozone loss in 2011,” Nature, vol. 478, no. 7370, pp. 469–475, 2011.
- R. R. Garcia, “Atmospheric science: an Arctic ozone hole?” Nature, vol. 478, no. 7370, pp. 462–463, 2011.
- M. J. Peak, J. G. Peak, M. P. Moehring, and R. B. Webb, “Ultraviolet action spectra for DNA dimer induction, lethality, and mutagenesis in Escherichia coli with emphasis on the UVB region,” Photochemistry and Photobiology, vol. 40, no. 5, pp. 613–620, 1984.
- C. Kielbassa, L. Roza, and B. Epe, “Wavelength dependence of oxidative DNA damage induced by UV and visible light,” Carcinogenesis, vol. 18, no. 4, pp. 811–816, 1997.
- M. F. Holick, “Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease,” The American Journal of Clinical Nutrition, vol. 80, no. 6, supplement, pp. 1678S–1688S, 2004.
- J. E. Dazard, H. Gal, N. Amariglio, G. Rechavi, E. Domany, and D. Givol, “Genome-wide comparison of human keratinocyte and squamous cell carcinoma responses to UVB irradiation: implications for skin and epithelial cancer,” Oncogene, vol. 22, no. 19, pp. 2993–3006, 2003.
- M. H. Karol, “How environmental agents influence the aging process,” Biomolecules and Therapeutics, vol. 17, no. 2, pp. 113–124, 2009.
- C. Toiron, A. Rumbero, E. Wollenweber, F. J. Arriaga, and M. Bruix, “A new skeletal triterpenoid isolated from Empetrum nigrum,” Tetrahedron Letters, vol. 36, no. 36, pp. 6559–6562, 1995.
- T. Jarevång, M. C. Nilsson, A. Wallstedt, G. Odham, and O. Sterner, “A bibenzyl from Empetrum nigrum,” Phytochemistry, vol. 48, no. 5, pp. 893–896, 1998.
- K. Ogawa, H. Sakakibara, R. Iwata et al., “Anthocyanin composition and antioxidant activity of the crowberry (Empetrum nigrum) and other berries,” Journal of Agricultural and Food Chemistry, vol. 56, no. 12, pp. 4457–4462, 2008.
- K. C. Kim, K. A. Kang, R. Zhang et al., “Risk reduction of ethyl acetate fraction of Empetrum nigrum var. japonicum via antioxidant properties against hydrogen peroxide-induced cell damage,” Journal of Toxicology and Environmental Health A, vol. 72, no. 21-22, pp. 1499–1508, 2009.
- K. C. Kim, I. K. Lee, K. A. Kang et al., “Empetrum nigrum var. japonicum extract suppresses γ-ray radiation-induced cell damage via inhibition of oxidative stress,” The American Journal of Chinese Medicine, vol. 39, no. 1, pp. 161–170, 2011.
- J. Carmichael, W. G. DeGraff, and A. F. Gazdar, “Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing,” Cancer Research, vol. 47, no. 4, pp. 936–942, 1987.
- A. R. Rosenkranz, S. Schmaldienst, K. M. Stuhlmeier, W. Chen, W. Knapp, and G. J. Zlabinger, “A microplate assay for the detection of oxidative products using 2′,7′-dichlorofluorescin-diacetate,” Journal of Immunological Methods, vol. 156, no. 1, pp. 39–45, 1992.
- I. Nicoletti, G. Migliorati, M. C. Pagliacci, F. Grignani, and C. Riccardi, “A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry,” Journal of Immunological Methods, vol. 139, no. 2, pp. 271–279, 1991.
- A. Cossarizza, M. Baccarani-Contri, G. Kalashnikova, and C. Franceschi, “A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5',6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazolcarbocyanine iodide (JC-1),” Biochemical and Biophysical Research Communications, vol. 197, no. 1, pp. 40–45, 1993.
- Y. Okimoto, A. Watanabe, E. Niki, T. Yamashita, and N. Noguchi, “A novel fluorescent probe diphenyl-1-pyrenylphosphine to follow lipid peroxidation in cell membranes,” FEBS Letters, vol. 474, no. 2-3, pp. 137–140, 2000.
- N. P. Singh, “Microgels for estimation of DNA strand breaks, DNA protein crosslinks and apoptosis,” Mutation Research, vol. 455, no. 1-2, pp. 111–127, 2000.
- R. Rajagopalan, S. K. Ranjan, and C. K. K. Nair, “Effect of vinblastine sulfate on γ-radiation-induced DNA single-strand breaks in murine tissues,” Mutation Research, vol. 536, no. 1-2, pp. 15–25, 2003.
- J. H. Lee and J. W. Park, “Protective role of α-phenyl-N-t-butylnitrone against Ionizing radiation in U937 cells and mice,” Cancer Research, vol. 63, no. 20, pp. 6885–6893, 2003.
- R. L. Levine, D. Garland, C. N. Oliver et al., “Determination of carbonyl content in oxidatively modified proteins,” Methods in Enzymology, vol. 186, pp. 464–478, 1990.
- A. van Laethem, S. van Kelst, S. Lippens et al., “Activation of p38 MAPK is required for Bax translocation to mitochondria, cytochrome c release and apoptosis induced by UVB irradiation in human keratinocytes,” The FASEB Journal, vol. 18, no. 15, pp. 1946–1948, 2004.
- D. Kulms and T. Schwarz, “Molecular mechanisms involved in UV-induced apoptotic cell death,” Skin Pharmacology and Applied Skin Physiology, vol. 15, no. 5, pp. 342–347, 2002.
- D. Kulms and T. Schwarz, “Independent contribution of three different pathways to ultraviolet-B-induced apoptosis,” Biochemical Pharmacology, vol. 64, no. 5-6, pp. 837–841, 2002.
- D. E. Heck, A. M. Vetrano, T. M. Mariano, and J. D. Laskin, “UVB light stimulates production of reactive oxygen species: unexpected role for catalase,” Journal of Biological Chemistry, vol. 278, no. 25, pp. 22432–22436, 2003.
- M. Ozawa, K. Ferenczi, T. Kikuchi et al., “312-nanometer ultraviolet B light (narrow-band UVB) induces apoptosis of T cells within psoriatic lesions,” Journal of Experimental Medicine, vol. 189, no. 4, pp. 711–718, 1999.
- S. Jackson, C. Harwood, M. Thomas, L. Banks, and A. Storey, “Role of Bak in UV-induced apoptosis in skin cancer and abrogation by HPV E6 proteins,” Genes and Development, vol. 14, no. 23, pp. 3065–3073, 2000.
- P. Brenneisen, H. Sies, and K. Scharffetter-Kochanek, “Ultraviolet-B irradiation and matrix metalloproteinases: from induction via signaling to initial events,” Annals of the New York Academy of Sciences, vol. 973, pp. 31–43, 2002.
- G. J. Fisher, S. Kang, J. Varani et al., “Mechanisms of photoaging and chronological skin aging,” Archives of Dermatology, vol. 138, no. 11, pp. 1462–1470, 2002.
- C. F. Garland, F. C. Garland, E. D. Gorham et al., “The role of vitamin D in cancer prevention,” American Journal of Public Health, vol. 96, no. 2, pp. 252–261, 2006.
- S. K. Katiyar, M. S. Matsui, C. A. Elmets, and H. Mukhtar, “Polyphenolic antioxidant (-)-epigallocatechin-3-gallate from green tea reduces UVB-induced inflammatory responses and infiltration of leukocytes in human skin,” Photochemistry and Photobiology, vol. 69, no. 2, pp. 148–153, 1999.
- A. Svobodová, J. Psotová, and D. Walterová, “Natural phenolics in the prevention of UV-induced skin damage. A review,” Biomedical Papers of the Medical Faculty of the University Palacky, vol. 147, no. 2, pp. 137–145, 2003.
- F. M. Strickland, J. M. Kuchel, and G. M. Halliday, “Natural products as aids for protecting the skin's immune system against UV damage,” Cutis, vol. 74, no. 5, pp. 24–28, 2004.
- M. Ding, R. Feng, S. Y. Wang et al., “Cyanidin-3-glucoside, a natural product derived from blackberry, exhibits chemopreventive and chemotherapeutic activity,” Journal of Biological Chemistry, vol. 281, no. 25, pp. 17359–17368, 2006.
- Z. Bing-Rong, J. Song-Liang, C. Xiao-E et al., “Protective effect of the Baicalin against DNA damage induced by ultraviolet B irradiation to mouse epidermis,” Photodermatology Photoimmunology and Photomedicine, vol. 24, no. 4, pp. 175–182, 2008.
- S. K. Jung, K. W. Lee, S. Byun, et al., “Myricetin suppresses UVB-induced skin cancer by targeting Fyn,” Cancer Research, vol. 68, no. 14, pp. 6021–6029, 2008.
- J. H. Huang, C. C. Huang, J. Y. Fang et al., “Protective effects of myricetin against ultraviolet-B-induced damage in human keratinocytes,” Toxicology in Vitro, vol. 24, no. 1, pp. 21–28, 2010.
- J. A. Nichols and S. K. Katiyar, “Skin photoprotection by natural polyphenols: anti-inflammatory, antioxidant and DNA repair mechanisms,” Archives of Dermatological Research, vol. 302, no. 2, pp. 71–83, 2010.
- D. Kulms, E. Zeise, B. Pöppelmann, and T. Schwarz, “DNA damage, death receptor activation and reactive oxygen species contribute to ultraviolet radiation-induced apoptosis in an essential and independent way,” Oncogene, vol. 21, no. 38, pp. 5844–5851, 2002.
- K. Nys, H. Maes, G. Andrei, R. Snoeck, M. Garmyn, and P. Agostinis, “Skin mild hypoxia enhances killing of UVB-damaged keratinocytes through reactive oxygen species-mediated apoptosis requiring Noxa and Bim,” Free Radical Biology & Medicine, vol. 52, no. 6, pp. 1111–1120, 2012.