Targeted Metabolomics of Serum Acylcarnitines Evaluates Hepatoprotective Effect of Wuzhi Tablet (Schisandra sphenanthera Extract) against Acute Acetaminophen Toxicity

Figure 2

WZ protects against APAP-induced liver toxicity. Serum AST and ALT enzyme levels of 2 h (a) or 24 h (b) serum samples from control, WZ-treated, WZ/APAP-treated, and APAP-treated mice (mean ± SD, 𝑛=5 in each group). *𝑃<0.05, **𝑃<0.005, ***𝑃<0.0001, NS: not significant.

(a)

(b)