Chinese Medicine Injection Shuanghuanglian for Treatment of Acute Upper Respiratory Tract Infection: A Systematic Review of Randomized Controlled Trials

Table 1

Characteristics of included studies.

Study ID	Number; (male/female)	Treatment/control	Disease	SHL intravenous; injection, dosage	Treatment; duration	Control	Outcome measure
Li 1996 [23]	103/67	86/84	Acute tonsillitis	60 mg/kg/d; (injection powder)	3 d	Penicillin	Fever resolution
Li and Jia 2000 [24]	35/53	50/38	Acute upper respiratory infection	1 mL/kg/d; (injection)	3 d	Ribavirin and lincomycin	Fever resolution after treatment; time to resolution of fever
Li 2002 [25]	53/42	48/47	Acute tonsillitis	60 mg/kg/d; (injection powder)	5 d	Penicillin	Fever resolution
Hong et al. 2003 [22]	73/50	62/61	Acute tonsillitis	60 mg/kg/d	5 d	Penicillin	Fever resolution
Zhang and Hu 2003 [27]	45/37	52/30	Acute upper respiratory infection	1 mL/kg/d, 20 mL (maximum) (injection)	3–7 d	Penicillin and ribavirin	No clear description
Liang 2007 [26]	54/36	49/41	Acute upper respiratory infection	60 mg/kg/d; (injection powder)	5 d	Ribavirin	Fever resolution
Gao and Xu 2010 [21]	77/53	68/62	Acute upper respiratory infection	60 mg/kg/d (injection powder)	5 d	Ribavirin	Fever resolution after treatment; time to resolution of fever, cough, and nasal congestion and discharge
Cui et al. 2012 [20]	57/22	41/38	Acute upper respiratory infection	60 mg/kg/d; (injection powder)	5 d	Ribavirin	Fever resolution after treatment; time to resolution of fever, cough, and sore throat