Ameliorative Effect of Hexane Extract of Phalaris canariensis on High Fat Diet-Induced Obese and Streptozotocin-Induced Diabetic Mice

Table 4

Effect of different extracts of P. canariensis on the lipid profiles and hepatic enzymes of normal and obese mice.

Group	NC	OC	OC + AL-H	OC + AL-C	OC + AL-M
Serum plasma
Total cholesterol (mg/dL)	70.3±1.3	120.5±5.4	74.0±3.2^a	71.4±4.2^a	72.6±2.5^a
HDL (mg/dL)	43±2.0	32.0±1.6	39.7±2.2^a	40.7±3.2^a	38.9±0.6^a
Triglycerides (mg/dL)	82.4±3.1	115.8±5.3	86.2±6.7^a	84.5±5.8^a	87.3±2.0^a
MDA (nmol MDA/mg protein)	0.05±0.00	0.08±0.00	0.06±0.00^a	0.05±0.00^a	0.06±0.00^a
Hepatic lipids
Cholesterol (μmol/g liver)	18.2±4.3	35.6±5.3	26.7±6.1^a	25.2±7.5^a	27.0±7.7^a
Triglyceride (μmol/g liver)	13.8±3.4	26.9±4.8	17.4±3.3^a	16.8±5.2^a	18.0±5.0^a
Hepatic enzymes
ALP (U/mL)	0.52±0.07	0.63±0.04	0.57±0.04	0.54±0.08	0.59±0.01
SGOT (U/mL)	1.79±0.08	2.01±0.05	1.86±0.03	1.84±0.05	10.88±0.02
SGPT (U/mL)	0.58±0.06	0.72±0.02	0.65±0.02	0.64±0.08	0.68±0.06

Each value represents mean ± S.E.M. (𝑛=10 animals in each group) ^a𝑃<0.05 versus obese control. Hexane extract (AL-H), chloroform extract (AL-C), and methanol extract (AL-M) from P. canariensis.