Ginsenoside Rb1 Protects Neonatal Rat Cardiomyocytes from Hypoxia/Ischemia Induced Apoptosis and Inhibits Activation of the Mitochondrial Apoptotic Pathway

Figure 2

Flow cytometry analysis of GS-Rb1 on cell death induced by H/I. (a) NRCMs were cotreated with or without GS-Rb1 (10, 20, and 40 μM) during H/I, for 24 h, and stained with Annexin V-fitc/PI. (b) Quantification of the percent of apoptotic and living cells in each group. Error bars represent mean±SD. ^∗∗∗𝑃<0.001 versus apoptotic cells in control group; ^###𝑃<0.001 versus living cells in control group; ⁺⁺𝑃<0.01 and ⁺⁺⁺𝑃<0.001 versus apoptotic cells in H/I group; ^&𝑃<0.05, ^&&𝑃<0.01, and ^&&&𝑃<0.001 versus living cells in H/I group (𝑛=3).

(a)

(b)