Ginsenoside Rb1 Protects Neonatal Rat Cardiomyocytes from Hypoxia/Ischemia Induced Apoptosis and Inhibits Activation of the Mitochondrial Apoptotic Pathway

Figure 6

Effect of GS-Rb1 on Bcl-2 and Bax changes induced by H/I. NRCMs were cotreated with or without GS-Rb1 (5, 10, 20, and 40 μM) during H/I for 24 h. (a) The protein levels of Bcl-2 and Bax were quantified by Western blot. (b) Quantitative data analysis for each group. (c) Bcl-2/Bax protein expression ratio in each group. Error bars represent mean ± SD. ^∗∗∗𝑃<0.001 versus Bcl-2 in control group; ^##𝑃<0.01 versus Bax in control group; ⁺𝑃<0.05, ⁺⁺𝑃<0.01, and ⁺⁺⁺𝑃<0.001 versus Bcl-2 in H/I group; ^&𝑃<0.05 and ^&&𝑃<0.01 versus Bax in H/I group.

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