Research Article

Neuroprotective Effects of Cuscutae Semen in a Mouse Model of Parkinson’s Disease

Figure 2

Effects of CS on the formation of reactive oxygen species (ROS) and glutathione (GSH) depletion due to MPP+. The PC12 cells (1 × 105 cells/mL) were treated with 1 mM MPP+ in the presence of CS (0.001, 0.01, 5, and 10 μg) for 24 h at 37°C. Formation of ROS was assayed by measuring fluorescence of dichlorofluorescein (DCF, a); GSH contents (μmol/mg protein) were determined using GSH reductase (b). Data are expressed as the mean ± S.E.M. , compared with control. , , compared with MPP+.
150153.fig.002a
(a)
150153.fig.002b
(b)