Effects of Chronic Electroacupuncture on Depression- and Anxiety-Like Behaviors in Rats with Chronic Neuropathic Pain
Figure 1
Chronic constriction injury (CCI) induced pain-like behavior. Thermal hyperalgesia and mechanical allodynia were measured before surgery, day 7, day 14, and day 21 after the CCI surgery, respectively. (a, b) Compared with the normal rats and sham controls, the rats subjected to CCI displayed significantly decreased PWL in the ipsilateral hind paw at 7, 14, and 21 days following the CCI surgery, but showed no reduction in the contralateral PWL at the same time point. (c, d) The mechanical threshold of CCI rats was statistically decreased in the ipsilateral hind paw at 7, 14, and 21 days after the surgery. There was no significant difference in either thermal or mechanical pain behaviors between the normal rats and sham controls. The data are expressed as the . ( versus normal group. versus sham surgery group).
