Research Article

Effects of Chronic Electroacupuncture on Depression- and Anxiety-Like Behaviors in Rats with Chronic Neuropathic Pain

Figure 3

Effects of EA and fluoxetine on the anxiety-like behaviors in CCI rats. Comparing with the normal rats, the rats subjected to CCI displayed a significant decrease in the percentage of open arm entries and the percentage of time spent in open arms at day 7 and day 21 after the CCI surgery. (a, b) Chronic EA at GV20–GB34 on CCI rats significantly elevated their percentage of open arm entries and the percentage of time spent in open arms. The data are expressed as the . ( versus normal rats. versus model group). (c, d) Chronic fluoxetine at either 10 or 30 mg/kg induced no statistically therapeutic effects on the behaviors of CCI rats in the EPM test. The data are expressed as the . ( versus normal rats. versus group).
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