Effects of Chronic Electroacupuncture on Depression- and Anxiety-Like Behaviors in Rats with Chronic Neuropathic Pain

Figure 5

CCI reduced the phosphorylation of hippocampus NR1 subunits. (a) Representative western blots showing the expression of pNR1, total NR1, and GAPDH in contralateral hippocampus. (b) Compared with the normal group and sham controls, the phosphorylation of NR1 was significantly reduced in the hippocampus of CCI rats at day 7 and day 21 after the CCI surgery (normalized by GAPDH). (c) The expression of total NR1 was not decreased in the hippocampus of CCI rats at the same time point (𝑛=3). The data are expressed as the mean±SEM. (^∗𝑃<0.05 versus normal group. ^#𝑃<0.05 versus sham surgery group).

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