Effects of a Proprietary Freeze-Dried Water Extract of Eurycoma longifolia (Physta) and Polygonum minus on Sexual Performance and Well-Being in Men: A Randomized, Double-Blind, Placebo-Controlled Study

Table 5

Effect of treatment on sexual intercourse assessment (SIA).

SIA questions	Baseline (mean ± SE)		6 weeks (mean ± SE)		12 weeks (mean ± SE)
	Active	Placebo	Active	Placebo	Active	Placebo
Was this the first attempt at sexual intercourse on this day?	1.00±0.00^a	0.97±0.026	0.98±0.023	0.98±0.017	0.96±0.038	0.99±0.009
Was foreplay or sexual activity initiated with the goal of sexual intercourse?	1.00±0.00^a	0.95±0.04	0.96±0.03	0.95±0.03	0.95±0.05	0.98±0.02
Did foreplay precede the attempted intercourse?	1.00±0.00^a	0.97±0.02	0.97±0.03	0.95±0.03	0.93±0.05^a	0.98±0.02
Were you able to achieve at least some erection?	1.00±0.00^a	0.95±0.05	0.98±0.02	0.95±0.02	1.00±0.00^b	0.97±0.02
Were you able to insert your entire penile shaft into your partner’s vagina?	0.71±0.11	0.42±0.13	0.84±0.07	0.64±0.09	0.96±0.02^b,c	0.62±0.13
Did your erection last long enough for you to have successful intercourse?	0.44±0.12	0.35±0.12	0.67±0.09^c	0.54±0.10	0.89±0.04^b	0.60±0.13
Elapsed time from erection perceived hard enough for penetration to withdrawal from your partner’s vagina (in minutes)?	7.47±2.06	7.06±1.82	11.81±2.65	7.27±1.67	19.56±3.93^c	12.28±3.17
Did you ejaculate while still in your partner?	0.29±0.11	0.33±0.12	0.52±0.10^c	0.53±0.12	0.62±0.11^c	0.65±0.12^c
Overall, were you satisfied with the hardness of your erection?	0.28±0.11^b	0.06±0.03	0.55±0.10^c	0.24±0.09	0.70±0.09^a,d	0.35±0.13^c
Overall, were you satisfied with this sexual experience?	0.33±0.10	0.33±0.13	0.61±0.10^c	0.44±0.11	0.87±0.06^b,e	0.52±0.14
Please rate the range of your erection during this sexual intercourse attempt.	2.54±0.22	2.14±0.23	2.95±0.22^c	2.68±0.15	3.54±0.11^a,d	2.87±0.27

^a𝑃<0.05 versus placebo at this time point.
^b𝑃<0.0005 versus placebo at this time point.
^c𝑃<0.05 versus baseline in the treatment group.
^d𝑃<0.005 versus baseline in the treatment group.
^e𝑃<0.0005 versus baseline in the treatment group.