Traditional Chinese Medicine Shuang Shen Ning Xin Attenuates Myocardial Ischemia/Reperfusion Injury by Preserving of Mitochondrial Function

Table 1

Theeffect of SSNX on serum LDH levels, MDA contents and GSH-Px activities after MI/R injury.

Groups	Dose, mg/kg	LDH, U/L	MDA, nmol/mg protein	GSH-Px, U/mg protein
Sham	—	489 ± 96	1.58 ± 0.25	29.93 ± 6.11
I/R	—	1843 ± 787^##	4.55 ± 0.81^##	16.14 ± 2.32^##
I/R + TMZ	10	911 ± 416**	1.89 ± 0.26**	24.77 ± 3.91*
I/R + SSNX	22.5	953 ± 271*	2.32 ± 0.89**	22.14 ± 4.47
I/R + SSNX	45	828 ± 301**	2.17 ± 0.49**	25.10 ± 5.52*

Note: LDH, 𝑛=8/group; MDA, 𝑛=6/group; GSH-Px, 𝑛=6/group; Date are shown as mean ± SD, ^##𝑃<0.01 versus Sham group, *𝑃<0.05, **𝑃<0.01 versus I/R group.