Akebia trifoliate (Thunb.) Koidz Seed Extract Inhibits the Proliferation of Human Hepatocellular Carcinoma Cell Lines via Inducing Endoplasmic Reticulum Stress

Figure 4

Effect of ATSE on the protein expression of ER stress-related biomarkers. The relative expression of ER-stress biomarkers at protein level after 72-hour treatment. GAPDH was used as internal control. G418 (0.45 mg/mL); ATSE: Akebia trifoliate seed extract (0.625 mg/mL); 1/2(G418 + ATSE): a combination of half dosage of each accordingly. (a) relative protein expression of HYOU1, (b) relative protein expression of HSP90AA1, (c) relative protein expression of SEC63, (d) relative expression of DNAJB11, (e) relative protein expression of GRP78, and (f) relative protein expression of HSPA9. The values given are the mean ± S.D. ; and (versus control group); and (versus G418 group).

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