Antihyperglycemic and Anti-Inflammatory Effects of Standardized Curcuma xanthorrhiza Roxb. Extract and Its Active Compound Xanthorrhizol in High-Fat Diet-Induced Obese Mice

Table 1

Effects of XAN and CXE treatments on body weight in HFD-induced obese mice.

Group	Initial body weight (g)	Final body weight (g)
ND	30.9 ± 2.3^##	40.6 ± 2.1^##
HFD	44.6 ± 3.3	52.0 ± 2.3
Met 100	45.0 ± 2.3	52.5 ± 2.2
XAN 10	44.4 ± 2.4	52.6 ± 3.2
XAN 25	43.9 ± 2.2	50.5 ± 1.6
CXE 50	44.5 ± 3.2	52.3 ± 2.1
CXE 100	45.4 ± 3.4	51.2 ± 1.5

Data are expressed as mean ± SD (𝑛=7). ^##𝑃<0.01 compared to the ND group. ND: normal diet, HFD: high-fat diet, Met 100: HFD with metformin 100 mg/kg/day, XAN 10 or 25: HFD with XAN 10 or 25 mg/kg/day, and CXE 50 or 100: HFD with CXE 50 or 100 mg/kg/day.