Targeting FASN in Breast Cancer and the Discovery of Promising Inhibitors from Natural Products Derived from Traditional Chinese Medicine

Table 3

Herbs with promoting health’s function with strong FASN inhibitory effect. Under TCM theory, the weakness of a healthy atmosphere in the human body is one of the major underlying pathologies for malignance occurrences. It has been more widely accepted to palliative therapy without the resection of tumor. This group of herbs is commonly used in combination with chemotherapy and radiotherapy to improve the patients overall health and increase tolerance of chemotherapy.

扶 正培 本 Promoting health	Chemical components	Pharmacological action
The root of Paeonia lactiflora Pall. (白 芍)	Paeoniflorin; Paeonol; Paeonin; Triterpenoids; Essential oils; Tannins	Antitumor, improve immune function; composed; analgesia; relieve fever; anti-inflammation
Cinnamomum cassia Presl (肉 桂)	Essential oils; Tannins, Mucoid substances; Resins	Antitumor, composed; analgesia
Polygonum multiflorum Thunb. (何 首烏)	Emodin; Chrysophanol; Rhein; Resveratrol; Catechin; Epicatechin; Piceid; Gallic acid	Improve immune function; lowering serum cholesterol; treatment of atherosclerosis
Fructus psoraleae (補 骨脂)	Essential oils; Saponins; Flavonoids; Astragalin; Bavachin; Monoterpenes; Resin; Stigmasterol;	Antitumor; bacteriostat
Drynaria fortunei (Kunze) J. Sm. (骨 碎補)	Hesperidin; Naringin; Sting-masterol; Triterpenes	Antitumor; promote bone calcium absorption; lowering serum cholesterol; composed; analgesia;
Epimedium brevicornum Maxim. (淫 羊藿)	Icariin; Phytosterol; Essential oils; Cetyl alcohol; Hentriacontane; Palmitic acid; Stearic acid; Linolenic acid; Bilobanol; Hyperin; Tannins	Antitumor; antibechic; enhance sexual function
Cynomorium ongaricum Rupr. (鎖 陽)	Tannins; Anthocyanin; Triterpenoid saponin	Enhance immune function; demulcent
Carica papaya L. (番 木瓜)	Papain; Carica; Rennet; Carotene	Inhibition of tumor growth
Eclipta prostrata L. (墨 旱蓮)	Tannins; Essential oils; Saponins; Ecliptine	Hematischesis