Research Article

The Anxiolytic Effects of Valtrate in Rats Involves Changes of Corticosterone Levels

Figure 4

Effect of valtrate on the behavior of rat in the OFT in a 10 min session in the open field performed 1 h after the administration of vehicle (p.o.), valtrate (5, 10, and 20 mg/kg, p.o.), and 0.5 h after the administration of diazepam (1 mg/kg, p.o.). (a) Number of central entries, (b) time spent in central area, and (c) total distance. Columns represent the means ± SEM, rats. * compared to the vehicle group.
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