Role of JNK Activation and Mitochondrial Bax Translocation in Allicin-Induced Apoptosis in Human Ovarian Cancer SKOV3 Cells
Figure 3
Effect of allicin and/or SP600125 on the phosphorylation of JNK in SKOV3 cells. (a) Treatment with various concentrations of allicin for 15 min. (b) Treatment with 25 μg/mL of allicin at indicated times. (c) Pretreatment with 20 μM SP600125 for 30 min before incubation with 25 μg/mL of allicin for 15 min; JNK phosphorylation was measured by western blot analysis after 48 h.