Puerarin Attenuates Cerebral Damage by Improving Cerebral Microcirculation in Spontaneously Hypertensive Rats

Figure 1

Effect of puerarin on brain microvascular remodeling in rats. (a)–(d) Brain microvascular remodeling. (a) Wistar-Kyoto (WKY) rats, (b) spontaneously hypertensive rats (SHRs), and (c) SHRs receiving puerarin (100 mg/kg puerarin) for 14 days by intraperitoneal injection. (d) SHRs receiving nimodipine (30 mg/kg) by gastrogavage for 14 days (serial sections (6 μm) were stained by hematoxylin and eosin ((h)–(e)) as described in text, ×100).

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