Research Article

Puerarin Attenuates Cerebral Damage by Improving Cerebral Microcirculation in Spontaneously Hypertensive Rats

Figure 4

Effect of puerarin on proliferation and activity of p42/44 mitogen-activated protein kinases (MAPKs) in microvascular endothelial cells (MECs). (a) MECs proliferation detected by [3H]-TdR incorporation. (b) Western blot analysis of phosphorylation of p42/44 MAPKs in MECs (upper panel). Equal protein loading was verified by reblotting with antitotal p42/44 MAPK antibody (lower panel). (c) Densitometry of the immunoblots shown in (a). Data are mean ± SD, * compared with SHRs control, # compared with puerarin treatment [100 ng], and .
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