Gastrodiae Rhizoma Ethanol Extract Enhances Pentobarbital-Induced Sleeping Behaviors and Rapid Eye Movement Sleep via the Activation of GABA_A-ergic Transmission in Rodents

Table 1

GREE reduced the sleep onset time and prolonged the sleep duration of sleep time induced by sub-hypnotic dosage of pentobarbital (28 mg/kg, i.p.).

Group	Dose (mg/kg)	No. falling asleep/total	Sleep time (min)
Control	0	5/12	20.5 ± 3.8
Muscimol	0.2		47.2 ± 2.
GERE	25	9/13	35.6 ± 2.
	50		39.6 ± 2.
	100		42.3 ± 4.

Each value represents the mean S.E.M. ( = 12–14). < 0.05 and < 0.005 compared to control.