Gardenia jasminoides Extract Attenuates the UVB-Induced Expressions of Cytokines in Keratinocytes and Indirectly Inhibits Matrix Metalloproteinase-1 Expression in Human Dermal Fibroblasts

Figure 4

Effects of plant extracts on mRNA expressions of inflammatory cytokines induced by UVB in HaCaT cells. In (a) and (b), HaCaT cells were irradiated with 5~15 mJ cm⁻² UVB. In (c) and (d), cells were irradiated with 10 mJ cm⁻² UVB in the absence or presence of plant extracts (10, 30, or 100 μg mL⁻¹) and then incubated for 24 h before mRNA analysis by qRT-PCR. GAPDH was used as the reference. Data are expressed as fold changes (means ± SEs; 𝑛=3). ^#𝑃<0.05 versus the unirradiated control. *𝑃<0.05 versus the vehicle control irradiated with UVB.

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