Antidiabetic and Antioxidative Effect of Jiang Tang Xiao Ke Granule in High-Fat Diet and Low-Dose Streptozotocin Induced Diabetic Rats

Table 3

Effect of JTXK granule on serum lipid profiles in DM rats.

Groups	Dose (g/kg)	TC; (mmol/L)	TG; (mmol/L)	HDL; (mmol/L)	LDL; (mmol/L)
Normal	—	1.77±0.10	0.52±0.05	0.57±0.03	0.27±0.03
DM	—	22.78±3.68^∗∗	7.33±2.07^∗∗	0.35±0.33^∗∗	9.33±1.62^∗∗
DM/pioglitazone	0.0015	14.93±2.98	1.95±0.33^##	0.46±0.05	5.04±1.09^#
DM/JTXK	9	15.27±3.40	3.14±0.93^#	0.59±0.09^#	5.23±1.27^#

Experimental details were described in Table 1. Rats were treated with either pioglitazone or JTXK granule for 4 weeks. After that, serum triglycerides (TG), total cholesterol (TC), low-density lipoprotein (LDL), and high-density lipoprotein (HDL) were measured. Values are expressed by means ± SE, with 𝑛=10. **𝑃<0.01 versus normal rats; ^#𝑃<0.05 and ^##𝑃<0.01 versus DM rats. Statistically significant differences were determined using a one-way ANOVA followed by Dunnett’s post hoc analysis.