Research Article
Seoritae Extract Reduces Prostate Weight and Suppresses Prostate Cell Proliferation in a Rat Model of Benign Prostate Hyperplasia
Table 2
Comparison of parameters in each group.
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
The mean prostate weight of the BPH group was significantly higher than that of the control group, whereas the means of the BPH + SE groups were significantly reduced compared to the BPH group. A significant increase in oxidative stress was found in the BPH group compared with the control group, and oxidative stress was significantly reduced in the two BPH + SE groups. A significant increase in the concentration of caspase-3 was found in the BPH group compared with the control group, and it was significantly decreased in the two BPH + SE groups. A significant increase in 5-alpha reductase activity was found in the BPH group compared with the control group, and it was significantly reduced in the two BPH + SE groups. BPH: benign prostatic hyperplasia group; BPH + SE1: BPH group treated with Seoritae extract (228 mg/kg); BPH + SE2: BPH group treated with Seoritae extract (457 mg/kg); SOD: superoxide dismutase; 8-OHdG: 8-hydroxy-2-deoxyguanosine. Significant difference () compared with the control group. Significant difference () compared with the BPH group. |