Paeonol Inhibits Proliferation of Vascular Smooth Muscle Cells Stimulated by High Glucose via Ras-Raf-ERK1/2 Signaling Pathway in Coculture Model

Figure 3

Effect of high glucose on VSMC proliferation in the coculture model. VECs were pretreated with high glucose concentration (35.5 mM) for 48 h and then cocultured with VSMCs for another 24 h to stimulate VSMC proliferation. ^#𝑃<0.05, ^##𝑃<0.01 versus NG (5.5 mM) coculture group; *𝑃<0.05 versus HG (35.5 mM) coculture group.