Antihypertensive Effect of Syzygium cumini in Spontaneously Hypertensive Rats

Figure 1

Effect of intravenous injections of the hydroalcoholic extract of Syzygium cumini leaves (HESC; 0.01 to 4.0 mg/kg) on the blood pressure of Wistar anesthetized rats. (a) Dose-dependent hypotensive effect of HESC. (b) Partial inhibition of the hypotension induced by HESC (0.5 mg/kg) by atropine (ATR). Acetylcholine (ACh, 1.0 μg/kg) was used as an agonist in the production of the hypotensive effect. The columns and vertical bars indicate the mean ± SEM, respectively ()    versus isotonic solution; versus ACh 1.0 µg/kg and versus HESC 0.5 mg/kg (ANOVA, Newman-Keuls test). MAP: mean arterial pressure.

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