Comparison of Electroacupuncture and Morphine-Mediated Analgesic Patterns in a Plantar Incision-Induced Pain Model

Figure 3

Comparison of analgesic patterns between EA and subcutaneous injection of morphine in incisional pain. (a) Summary of the protocols used in this experiment. BL: baseline on one day before PI; D: postplantar incision day; EA: electroacupuncture; h: hour; s.c.: subcutaneous injection; Mor: morphine, marked with a blank triangle; PI: plantar incision, marked with a solid triangle; pre: before daily Mor i.p. and EA treatment. (b) Mechanical allodynia, PI: group for PI surgery, EA+PI: group for PI with repeated EA treatments, and Mor+PI: group for PI with repeated morphine s.c. injections; # < 0.05, ## < 0.01, ### < 0.001 groups versus PI; ∗∗ < 0.01, ∗∗∗ < 0.001 Mor+PI versus EA+PI; one-way ANOVA with Tukey’s multiple comparison test. (PI), 9 (EA+PI), and 6 (Mor+PI).

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