Pien Tze Huang Overcomes Multidrug Resistance and Epithelial-Mesenchymal Transition in Human Colorectal Carcinoma Cells via Suppression of TGF-β Pathway

Figure 1

Effect of PZH on the viability of 5-FU resistant colorectal cancer cells. Cell viability was determined by MTT assay after HCT-8/5-FU and parental HCT-8 cells were treated with the indicated concentrations of 5-FU (a), ADM (b), and PZH (c) for 48 h. The data were normalized to the viability of control cells. Data are averages with S.D. (error bars) from at least three independent experiments. , versus controls; , versus HCT-8/5-FU cells.

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