Treatment of Posttraumatic Stress Disorder Using the Traditional Japanese Herbal Medicine Saikokeishikankyoto: A Randomized, Observer-Blinded, Controlled Trial in Survivors of the Great East Japan Earthquake and Tsunami

Figure 2

(a) Change in the IES-R avoidance subscale score. (b) Change in the IES-R hyperarousal subscale score. (c) Change in the IES-R intrusion subscale score. Two-way ANOVA showed that each subscale differed significantly between the groups ((a) 𝑃=0.025, (b) 𝑃=0.005, (c) 𝑃=0.001). Post hoc testing showed that all subscale scores changed significantly from baseline to the endpoint in the SKK group ((a) 𝑃=0.003, (b) 𝑃<0.001, and (c) 𝑃<0.001), whereas in the control group, only the avoidance subscale score showed a significant change ((a) 𝑃=0.032, (b) n.s., and (c) n.s.).

(a)

(b)

(c)