Review Article

Botanical, Pharmacological, Phytochemical, and Toxicological Aspects of the Antidiabetic Plant Bidens pilosa L.

Figure 5

The underlying mechanism of the crude extract of B. pilosa (BP) and its active compound, compound 19 (CP), in T2D. BP and/or CP can treat T2D development via control of β cell function in db/db mice. Their anti-diabetic actions are through upregulation of insulin expression/secretion and protection of β cells involving secondary messengers (calcium and diacylglycerol) and their downstream PKCα pathway.
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