Validation of the Antidiabetic and Hypolipidemic Effects of Clitocybe nuda by Assessment of Glucose Transporter 4 and Gluconeogenesis and AMPK Phosphorylation in Streptozotocin-Induced Mice

Figure 3

Histology of liver tissue of mice in the (a) control (CON), (b) streptozotocin + vehicle (distilled water) (STZ), (c) STZ + C1, (d) STZ + C2, (e) STZ + C3, or (f) STZ + metformin (Metf) groups by hematoxylin and eosinstain. Magnification: 10 (ocular) × 20 (object lens). Mice treated with the streptozotocin + vehicle (distilled water) (STZ) group. C1, C2, and C3: extracts of Clitocybe nuda (C1: 0.2, C2: 0.5, and C3: 1.0 g/kg bodyweight); Metf: metformin (0.3 g/kg body weight).

(a)

(b)

(c)

(d)

(e)

(f)