Research Article

Antiviral Activity of Sulfated Polysaccharide of Adenanthera pavonina against Poliovirus in HEp-2 Cells

Table 1

The antiviral activity of the Adenanthera pavonina sulfated polysaccharide (SPLSAp) against poliovirus. Evaluation under the assays of the time of addition (0 h), virucidal, and inhibition of adsorption, monitored by plaque reduction assay (PRA).

AssayPV-1
SIc

Time of addition (0 h)5001.18423.73
Virucidal 50016.47 30.54
Inhib. of adsorption 500 25.2519.80

Fifty percent cytotoxic concentration (µg/mL).
bFifty percent inhibitory concentration (µg/mL).
cSelective index (CC50/IC50).