Research Article
Cytotoxic Activities against Breast Cancer Cells of Local Justicia gendarussa Crude Extracts
Table 3
Percentage viability of MDA-MB-468 cells in leaf extracts from five different locations.
| Concentration (μg/mL) | 7.81 | 15.63 | 31.25 | 62.5 | 125 | 250 | 500 | 1000 |
| Leaf extract from Mersing | 92.63 ± 0.04 | 76.53 ± 0.02 | 14.21 ± 0.02 | 7.13 ± 0.01 | 3.78 ± 0.01 | 3.63 ± 0.01 | 3.38 ± 0.01 | 6.91 ± 0.01 |
| Leaf extract from Muar | 79.53 ± 0.03 | 74.33 ± 0.02 | 69.20 ± 0.09 | 75.0 ± 0.03 | 63.7 ± 0.01 | 22.63 ± 0.02 | 3.03 ± 0.01 | 2.49 ± 0.01 |
| Leaf extract from Skudai | 98.03 ± 0.082 | 101.67 ± 0.021 | 97.87 ± 0.016 | 82.9 ± 0.021 | 77.0 ± 0.014 | 52.33 ± 0.045 | 4.83 ± 0.002 | 4.43 ± 0.01 |
| Leaf extract from Batu Pahat | 96.26 ± 0.02 | 92.06 ± 0.03 | 91.23 ± 0.09 | 89.0 ± 0.04 | 102.46 ± 0.06 | 64.61 ± 0.08 | 7.07 ± 0.01 | 6.19 ± 0.01 |
| Leaf extract from Pulai | 92.96 ± 0.03 | 88.68 ± 0.03 | 87.69 ± 0.02 | 86.4 ± 0.01 | 82.6 ± 0.04 | 77.53 ± 0.04 | 36.8 ± 0.07 | 8.12 ± 0.01 |
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Values are mean ± STDEV for 3 replicates < 0.05, < 0.01, and < 0.001 compared to control (untreated cell).
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