Yiqi Huoxue Recipe Improves Heart Function through Inhibiting Apoptosis Related to Endoplasmic Reticulum Stress in Myocardial Infarction Model of Rats
Figure 1
Yiqi Huoxue recipe attenuates heart function injury and attenuates the heart to body weight ratio in myocardial infarcted rats model. Rats were operated with myocardial infarction (MI) surgery and after 4 weeks of treatment, echocardiography assay was performed ((a) sham, (b) MI, (c) MI + Metoprolol Tartrate, (d) MI + Yiqi Huoxue recipe, and (e) anatomic and echocardiographic data for rats 4 weeks after myocardial infarction with different treatment). And after sacrificing the rats, the heart to body weight ratio was also calculated. In the rat myocardial infarction (MI) model, the heart to body weight ratio is increased in the untreated MI group at 4 weeks after MI. Yiqi Huoxue recipe and MT treatment diminished the effect (e). As to the echocardiographic data, the LVEF and LVFS showed the same trend (e). Values are mean ± SD (), LVEF, left ventricular ejection fraction; LVFS, left ventricular fractional shortening; LVDd, left ventricular end-diastolic volume; LVDs, left ventricular end-systolic volume. , versus sham group. versus myocardial infarction group.
