Caffeic Acid Phenethyl Ester: Consequences of Its Hydrophobicity in the Oxidative Functions and Cytokine Release by Leukocytes
Figure 5
Caffeic acid, its derivatives, and apocynin (apo) as inhibitors of the production of superoxide anion by stimulated PMN and xanthine/xanthine oxidase. (a, b) Lucigenin-dependent chemiluminescence elicited by opsonised zymosan-activated PMN. (c) WST-1 reduction elicited by PMA-activated PMN. (d) WST-1 reduction elicited by xanthine/xanthine oxidase. The results are mean and SEM of duplicates of three different experiments. Different letters denote significant differences. One-way ANOVA and Tukey’s multiple comparison test, .