Table 2: Least square means and standard errors from mixed linear model analysis comparing GI and UC groups.

MeasurementGI 
Mean (SE) 
UC 
Mean (SE) 
P values*

PSS
 Baseline20.30 (1.41)19.23 (1.36)
 Time 216.89 (1.42)19.99 (1.37)0.012
 Time 317.11 (1.42)17.48 (1.37)0.381
STAI-S
 Baseline39.59 (2.32)39.35 (2.24)
 Time 236.42 (2.38)39.10 (2.27)0.382
 Time 336.38 (2.35)34.44 (2.30)0.606
STAI-T
 Baseline43.79 (2.32)43.14 (2.26)
 Time 239.69 (2.36)44.45 (2.26)0.041
 Time 339.11 (2.34)39.35 (2.28)0.735
BFI Total
 Baseline5.26 (0.43)4.55 (0.42)
 Time 24.04 (0.44)4.59 (0.42)0.040
 Time 33.60 (0.44)3.87 (0.43)0.104

Median (minimum and maximum) 
pg/mL 
Median (minimum and maximum) 
pg/mL 

CRH
 Baseline0.97 (0.03, 5.75)0.85 (0.03, 9.49)
 Time 28.80 (1.06, 47.32)8.30 (3.35, 85.29)
 Time 336.47 (4.90, 87.17)45.14 (2.78, 146.87)

P values from mixed-effects linear model comparing the GI group change from baseline to 8 weeks and 12 weeks with the corresponding UC group change from baseline to 8 and 12 weeks.
P values from mixed-effects linear model using the log CRH.