The Correlation between Chemical Composition, as Determined by UPLC-TOF-MS, and Acute Toxicity of Veratrum nigrum L. and Radix paeoniae alba

Figure 8

SH-SY5Y cell viability: SH-SY5Y cells were cultured with (a) veratridine (25–800 μM), (b) paeoniflorin (50−2000 μM), and (c) 400 μM veratridine in combination with 50−2000 μM paeoniflorin for 24 h. Cell viability was then assessed using MTS assays. Data are presented as mean±S.D. Means of three independent experiments, Asterisks indicate a statistically significant difference compared with untreated cells. ^∗𝑃<0.05; ^∗∗𝑃<0.01; ^∗∗∗𝑃<0.001 versus controL.

(a)

(b)

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